Invention Grant
- Patent Title: Inhibitors of the linear ubiquitin chain assembly complex (LUBAC) and related methods
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Application No.: US14774478Application Date: 2014-03-11
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Publication No.: US09783586B2Publication Date: 2017-10-10
- Inventor: Louis M. Staudt , Yibin Yang , Federico Bernal , Amanda L. Whiting
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2014/023006 WO 20140311
- International Announcement: WO2014/150350 WO 20140925
- Main IPC: C07K14/47
- IPC: C07K14/47 ; G01N33/574 ; C12Q1/68 ; A61K38/00 ; C12N9/00 ; A61K38/17 ; A61K45/06 ; A61N5/10
Abstract:
The invention relates to peptide inhibitors of linear ubiquitin chain assembly complex (LUBAC) and to methods of treating diseases including activated B-cell like diffuse large B cell lymphoma (ABC DLBCL) and autoimmune or inflammatory disorders.
Public/Granted literature
- US20160031957A1 INHIBITORS OF THE LINEAR UBIQUITIN CHAIN ASSEMBLY COMPLEX (LUBAC) AND RELATED METHODS Public/Granted day:2016-02-04
Information query
