Invention Grant
- Patent Title: PCR methods for characterizing the 5′ untranslated region of the FMR1 and FMR2 genes
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Application No.: US14191128Application Date: 2014-02-26
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Publication No.: US09783848B2Publication Date: 2017-10-10
- Inventor: Gary J. Latham , Liangjing Chen , Sachin Sah
- Applicant: ASURAGEN, INC.
- Applicant Address: US TX Austin
- Assignee: Asuragen, Inc.
- Current Assignee: Asuragen, Inc.
- Current Assignee Address: US TX Austin
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
This disclosure relates to methods of determining the presence and position of AGG or interruptor elements within a trinucleotide (for example, CGG) repeat region, and to methods of determining the number of repeats present in this region, by amplifying a set of products with a set of primers of which at least one comprises a portion of the CGG repeat region, and resolving the products to produce a representation of product size and abundance.
Public/Granted literature
- US20140248625A1 PCR METHODS FOR CHARACTERIZING THE 5' UNTRANSLATED REGION OF THE FMR1 AND FMR2 GENES Public/Granted day:2014-09-04
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