A touch screen control method and device are provided. The method includes acquiring a plurality of actual capacitance values of respective test points on a touch screen, identifying the interference level of an electrically conductive liquid according to differences between the actual capacitance values and a plurality of reference capacitance values of the respective test points, and controlling the touch screen under an operation mode corresponding to the interference level. The reference capacitance values are capacitance values of the respective test points when the test points are not influenced by an electrically conductive medium.