In embodiments of wireless radios managed based on proximity, a mobile device, such as a mobile phone, tablet computer, or other portable device can be implemented for multiple, different wireless communications. A mobile device can include a first radio system for a first wireless communications technology, and a second radio system for a second wireless communications technology. A connection manager determines, based on the first wireless communications technology, whether the mobile device is in an area that is proximate an endpoint implemented for the second wireless communications technology. The connection manager can turn-on the second radio system to enable wireless communication with the endpoint when the mobile device is in the area proximate the endpoint. Alternatively, the connection manager can turn-off the second radio system and conserve power that would otherwise be utilized to scan for the endpoint when the mobile device is not in the area proximate the endpoint.