A device for opening and closing an outwardly opening pivoting wing, comprising: an actuating device including a support, a crank rotatable relative to the support and a control mechanism operated by the crank, and an arm having a toothed portion which cooperates with said control mechanism, wherein the control mechanism cooperates with the toothed portion of the arm for the translational motion of the arm along a rectilinear direction between a locked wing position and an unlocked wing position, and vice versa, a first and a second slider intended to engage a groove of the wing in a movable manner in a rectilinear direction, wherein the first slider is articulated at a distal end of the arm and wherein the second slider is connected to a locking device.