A cleaning application that can clean, for one or more user profiles, at least one of one or more files of a computer or a registry of the computer is provided. The cleaning application can include a cleaning module. The cleaning module can select a plurality of user profiles of the computer. The cleaning module can further select at least one of a file location or a user profile hive for each user profile of the plurality of user profiles. The cleaning module can further clean at least one of one or more files stored within the file location or a registry stored within the user profile hive for each user profile of the plurality of user profiles.