Invention Grant
- Patent Title: Haemostatic wound dressing
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Application No.: US14376023Application Date: 2013-02-01
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Publication No.: US09808553B2Publication Date: 2017-11-07
- Inventor: Greg Walker , Sarah Margaret Middleton
- Applicant: Haemostatix Limited
- Applicant Address: GB Nottingham, Nottinghamshire
- Assignee: HAEMOSTATIX LIMITED
- Current Assignee: HAEMOSTATIX LIMITED
- Current Assignee Address: GB Nottingham, Nottinghamshire
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: GB1201751.3 20120201
- International Application: PCT/GB2013/050237 WO 20130201
- International Announcement: WO2013/114132 WO 20130808
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K9/00 ; A61L24/00 ; A61L15/32 ; A61L15/42 ; A61L15/44 ; A61L24/10

Abstract:
Haemostatic wound dressings are described. The dressings comprise a non-colloidal porous dressing material, and a plurality of fibrinogen-binding peptides immobilised to the non-colloidal porous dressing material, wherein each fibrinogen-binding peptide comprises: an amino acid sequence Gly-Pro-Arg-Xaa (SEQ ID NO: 1) at an amino-terminal end of the peptide, wherein Xaa is any amino acid other than Val, preferably Pro, Sar, or Leu; or an amino acid sequence Gly-His-Arg-Xaa (SEQ ID NO: 2) at an amino-terminal end of the peptide, wherein Xaa is any amino acid other than Pro. The dressings are able to accelerate haemostasis without requiring enzymatic activity. In particular, the dressings to do not rely on the action of exogenous thrombin, and can be stored long-term at room temperature in solution. Methods of making the dressings, and use of the dressings to control bleeding are also described.
Public/Granted literature
- US20150071985A1 HAEMOSTATIC WOUND DRESSING Public/Granted day:2015-03-12
Information query
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