Invention Grant
- Patent Title: Isoquinoline compounds, a process for their preparation, and pharmaceutical compositions containing them
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Application No.: US15119173Application Date: 2015-02-20
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Publication No.: US09809553B2Publication Date: 2017-11-07
- Inventor: Stéfano Chimenti , Christine Courchay , Aimee Dessinges , Françoise Gellibert , Bertrand Goument , Marc Konnert , Jean-Louis Peglion , Christophe Poitevin , Jean-Paul Vilaine , Nicole Villeneuve
- Applicant: LES LABORATOIRES SERVIER
- Applicant Address: FR Suresnes
- Assignee: LES LABORATOIRES SERVIER
- Current Assignee: LES LABORATOIRES SERVIER
- Current Assignee Address: FR Suresnes
- Agency: Hueschen and Sage
- Priority: FR1451389 20140221
- International Application: PCT/FR2015/050415 WO 20150220
- International Announcement: WO2015/124877 WO 20150827
- Main IPC: C07D217/02
- IPC: C07D217/02 ; C07D217/04 ; C07D405/06 ; A61K31/472 ; C07D217/24

Abstract:
A compound of formula (I): wherein the substituents are as defined in the description. Medicinal products containing the same which are useful in treating or preventing pathologies which are the result of activation of the RhoA/ROCK pathway and phosphorylation of the myosin light chain.
Public/Granted literature
- US20170137385A1 ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Public/Granted day:2017-05-18
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