Invention Grant
- Patent Title: Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA
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Application No.: US14531913Application Date: 2014-11-03
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Publication No.: US09809819B2Publication Date: 2017-11-07
- Inventor: Bob D. Brown
- Applicant: Dicerna Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: DICERNA PHARMACEUTICALS, INC.
- Current Assignee: DICERNA PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: MH2 Technology Law Group, LLP
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; C07H21/02
Abstract:
This invention relates to compounds, compositions, and methods useful for reducing KRAS target RNA and protein levels via use of Dicer substrate siRNA (DsiRNA) agents possessing asymmetric end structures.
Public/Granted literature
- US20150057337A1 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF KRAS BY ASYMMETRIC DOUBLE-STRANDED RNA Public/Granted day:2015-02-26
Information query
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