A display panel and a method for manufacturing the same and a display device are disclosed, the display panel comprises an array substrate (10) and a cell-assembled substrate (20) arranged oppositely to the array substrate (10), spacers spaced from each other are arranged between the array substrate (10) and the cell-assembled substrate (20), the spacers comprise a plurality of primary spacers (31); and M, in number, of the primary spacers (31) are provided per unit area in a peripheral region of the display panel, N, in number, of the primary spacers (31) are provided per unit area in a central region of the display panel, and M is greater than (>) N. The display panel can avoid the breakage of the spacers in the peripheral region of the display panel or the breakage of the orientation layer on the spacers.