A digital image processing circuit processes macro-pixels of a digital image. A gain control parameter of each pixel of the macro-pixel of the digital image is determined based on a location of the pixel in the digital image. Relative pixel positions of the pixels of the macro-pixel are determined, the relative pixel positions representing pixel positions with respect to color grids. A gain value of each pixel of the macro-pixel is determined based on the relative pixel positions. The gain values are modified based on the gain control parameters. The modified gains are applied to the pixels of the macro-pixel.