A multi-layer or single layer antifouling coating system. A multi-layer coating system comprises (a) a base coating for coating a substrate, and (b) an antifouling coating composition adapted to be disposed over the base coating, the antifouling coating composition comprising a functionalized polymer, and a curable polyether-containing silane of the Formula (1): (R1O)a(R1)(3-a)Si—R2—(Si(R1)2O)p—Si(R1)2—R2—O—(CH2—CHR1—O)q—R1 (1) where a is 1-3; R1 is H or alkyl radical from C1-C10; R2 is alkylene from C2-C10; p is 1-100; and q is 1-50. The base coating composition can comprise an epoxy modified adhesion promoter. Additionally, the anti-fouling coating composition can comprise an acetoxy, alkoxy, and/or ketoxime functional adhesion promoter.