The present invention provides an AMOLED pixel driving circuit and a pixel driving method. The AMOLED pixel driving circuit utilizes the 5T1C structure and comprises a first, a second, a third, a fourth and a fifth thin film transistors (M1, M2, M3, M4 and M5), a capacitor (C1) and an organic light emitting diode (D1). The AMOLED pixel driving circuit directly acquires a threshold voltage of the fourth thin film transistor (M4), i.e. the drive thin film transistor to implement threshold voltage compensation; by inputting the data signal (Data) to the source of the fourth thin film transistor (M4), i.e. the drive thin film transistor, the circuit reads the data signal (Data) at the same time while acquiring the threshold voltage of the drive thin film transistor to promote the working efficiency of the circuit; by setting one end of the capacitor (C1) to be coupled to a gate of the fourth thin film transistor (M4), i.e. the drive thin film transistor, and the other end to be coupled to the earth (GND), the signal input of the capacitor end can be reduced to simplify the required input signal.