Invention Grant
- Patent Title: Method for producing composition for external use containing physiologically acceptable salt of tranexamate
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Application No.: US13814549Application Date: 2011-07-15
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Publication No.: US09833401B2Publication Date: 2017-12-05
- Inventor: Masayoshi Miyamoto , Tomomi Kuromiya , Daisuke Suzuki
- Applicant: Masayoshi Miyamoto , Tomomi Kuromiya , Daisuke Suzuki
- Applicant Address: FR Neuilly sur Seine
- Assignee: CHANEL PARFUMS BEAUTE
- Current Assignee: CHANEL PARFUMS BEAUTE
- Current Assignee Address: FR Neuilly sur Seine
- Agency: Young & Thompson
- Priority: JP2010-177580 20100806
- International Application: PCT/IB2011/001865 WO 20110715
- International Announcement: WO2012/017313 WO 20120209
- Main IPC: A61K8/81
- IPC: A61K8/81 ; A61K8/41 ; A61K8/73 ; A61Q19/02 ; A61K8/00 ; A61K8/84 ; A61K8/02

Abstract:
A composition for external use containing a tranexamate as an active ingredient with suppressed sticky or oily feeling but having a fresh feel of use, and a method for producing the same. A tranexamate salt can be dispersed stably in an aqueous medium by (a) dissolving the tranexamate salt and an amphiphilic polymer in water, a water-soluble organic solvent or a mixture thereof; and (b) adding a mixed solution obtained in the step (a) to an aqueous medium, and thus keeping the tranexamate salt in molecular assembly particles formed of the amphiphilic polymer.
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