Invention Grant
- Patent Title: Method for activating helper T cell
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Application No.: US14652298Application Date: 2013-12-16
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Publication No.: US09833493B2Publication Date: 2017-12-05
- Inventor: Hiroshi Kubo , Shinji Sogo , Haruo Sugiyama
- Applicant: OTSUKA PHARMACEUTICAL CO., LTD. , INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC.
- Applicant Address: JP Osaka
- Assignee: International Institute of Cancer Immunology, Inc.
- Current Assignee: International Institute of Cancer Immunology, Inc.
- Current Assignee Address: JP Osaka
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: JP2012-274494 20121217
- International Application: PCT/JP2013/083580 WO 20131216
- International Announcement: WO2014/098012 WO 20140626
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61K35/15 ; C07K14/74 ; C12N5/0783 ; A61K35/17 ; A61K39/00
Abstract:
The present invention relates to a method for activating helper T cells, which includes the step of activating helper T cells by adding a WT1 peptide to antigen presenting cells, wherein the WT1 peptide has the ability to bind to an MHC class II molecule selected from HLA-DRB1*08:02 molecule, an HLA-DRB1*13:02 molecule, an HLA-DRB1*14:03 molecule, an HLA-DRB1*14:05 molecule, an HLA-DQB1*03:02 molecule, and an HLA-DQB1*04:01 molecule.
Public/Granted literature
- US20150328278A1 METHOD FOR ACTIVATING HELPER T CELL Public/Granted day:2015-11-19
Information query
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