A vehicle lower portion structure that includes: a suspension member that does not have a section that interconnects, in a vehicle width direction, a vehicle front-side end portion of a side rail placed on one vehicle width direction side and a vehicle front-side end portion of a side rail placed on the other vehicle width direction side; and a pair of right and left coupling portions that respectively interconnect the vehicle front-side end portion of the side rail placed on the one vehicle width direction side and a heat exchanger support lower member and interconnect the vehicle front-side end portion of the side rail placed on the other vehicle width direction side and the heat exchanger support lower member.