- Patent Title: Anti-PD1 antibodies and their use as therapeutics and diagnostics
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Application No.: US14736966Application Date: 2015-06-11
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Publication No.: US09834606B2Publication Date: 2017-12-05
- Inventor: Kang Li , Tong Zhang , Jing Song , Lanlan Xu , Qi Liu , Hao Peng
- Applicant: BeiGene, Ltd.
- Applicant Address: KY
- Assignee: BEIGENE, LTD
- Current Assignee: BEIGENE, LTD
- Current Assignee Address: KY
- Agency: Cooley LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61K39/00
Abstract:
Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) and inhibit PD1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD1-mediated functions.
Public/Granted literature
- US20150315274A1 Anti-PD1 Antibodies and their Use as Therapeutics and Diagnostics Public/Granted day:2015-11-05
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