A method for correcting flickers in a single-shot multiple-exposure image and associated apparatus is provided. The single-shot multi-exposure image includes first image data and second image data. The method includes the steps of: computing a first vertical profile for the first image data and a second vertical profile for the second image data; computing a flicker modulation function according to the first vertical profile and the second vertical profile; and multiplying each pixel in the second image data by the flicker modulation function to correct flickers.