Invention Grant
- Patent Title: Method of improving cognition and social behavior in humans having deficits therein due to neurodegenerative disorders and compounds and compositions therefor
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Application No.: US14625170Application Date: 2015-02-18
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Publication No.: US09849134B2Publication Date: 2017-12-26
- Inventor: Mehrdad Shamloo , Bitna Yi , Pooneh Memar Ardestani
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Bozicevic, Field & Francis LLP
- Agent Glenn J. Foulds
- Main IPC: C07D265/32
- IPC: C07D265/32 ; A61K31/17 ; A61K31/5375 ; A61K9/00 ; A61K9/08 ; A61K47/48 ; G01N33/50
Abstract:
A β1-ADR agonist prodrug compound, which is hydrolysable in vivo to release a β1-ADR agonist compound, and which prodrug compound contains a group which imparts greater lipophilicity and CNS bioavailability to the prodrug compound relative to the β1-ADR agonist compound.
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