A system for securely locking a storage box in a bed for a pickup truck, includes a storage box housing, a storage box lid and a lock for the lid. A plurality of wheels align with dips in the bottom of the truck bed. Guide pins align with a dip to keep the storage box housing centered. Horizontal locking pins are positioned inside the housing having both a retracted position and a locking position, in which each locking pin is partly into the nearest side wall. At least one vertical locking pin is positioned inside the housing having both a retracted position and a locking position partly within a hole in the ridge of the bottom wall. Once locking pins are engaged, they can only be disengaged from inside the housing when the lid for the storage box is open. Various holes are reinforced.