Invention Grant
- Patent Title: Inhibitors of ACK1/TNK2 tyrosine kinase
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Application No.: US14910486Application Date: 2014-08-06
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Publication No.: US09850216B2Publication Date: 2017-12-26
- Inventor: Nupam P. Mahajan , Kiran N. Mahajan , Nicholas J. Lawrence , Harshani R. Lawrence
- Applicant: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- Applicant Address: US FL Tampa
- Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
- Current Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
- Current Assignee Address: US FL Tampa
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2014/049935 WO 20140806
- International Announcement: WO2015/021149 WO 20150212
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07D239/49 ; C07D405/12 ; C07D239/42 ; C07D239/48 ; C07C53/18
Abstract:
Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of Ack1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new Ack1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I through IV are disclosed.
Public/Granted literature
- US20160176826A1 INHIBITORS OF ACK1/TNK2 TYROSINE KINASE Public/Granted day:2016-06-23
Information query
