- Patent Title: Sulfated and unsulfated flavonoid oligomers as cancer therapeutics
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Application No.: US15034232Application Date: 2014-11-07
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Publication No.: US09850221B2Publication Date: 2017-12-26
- Inventor: Umesh R. Desai , Rajesh Karuturi , Bhaumik B. Patel , Nirmita J. Patel
- Applicant: VIRGINIA COMMONWEALTH UNIVERSITY
- Applicant Address: US VA Richmond
- Assignee: VIRGINIA COMMONWEALTH UNIVERSITY
- Current Assignee: VIRGINIA COMMONWEALTH UNIVERSITY
- Current Assignee Address: US VA Richmond
- Agency: Whitham, Curtis & Cook, P.C.
- International Application: PCT/US2014/064481 WO 20141107
- International Announcement: WO2015/069979 WO 20150514
- Main IPC: C07D311/30
- IPC: C07D311/30 ; C07D405/12 ; C07D407/12
Abstract:
Sulfated and unsulfated flavonoid oligomers as inhibitors of cancer stem cells (CSCs) are provided. In particular, sulfated flavonoid dimers are shown to selectively inhibit CSCs growth and self-renewal both in vitro and in vivo.
Public/Granted literature
- US20160280676A1 SULFATED AND UNSULFATED FLAVONOID OLIGOMERS AS CANCER THERAPEUTICS Public/Granted day:2016-09-29
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