Invention Grant
- Patent Title: PDE9 inhibitors with imidazo triazinone backbone
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Application No.: US15358168Application Date: 2016-11-22
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Publication No.: US09850249B2Publication Date: 2017-12-26
- Inventor: Niels Svenstrup , Klaus Bæk Simonsen , Lars Kyhn Rasmussen , Karsten Juhl , Morten Langgård , Kate Wen , Yazhou Wang
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: DT Ward, PC
- Agent Donna T. Ward; Heng Zhu
- Priority: WOPCT/CN2012/070718 20120126; WOPCT/CN2012/080208 20120816
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/53

Abstract:
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).
Public/Granted literature
- US20170081333A1 PDE9 Inhibitors with Imidazo Triazinone Backbone Public/Granted day:2017-03-23
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