A system and method may obtain a connection profile, the connection profile including at least one rule related to at least one PII data element; associate the connection profile with a network connection; receive a data unit transmitted over the network connection, the data unit including at least a portion of the PII data element; and, based on the rule, perform at least one of: blocking transmission of the data unit, modifying the data unit, forwarding at least a portion of the data unit to a selected destination, storing the data unit, storing metadata related to the data unit, and reporting an event related to the data unit. A system and method may associate the connection profile with a set of connection. A system and method may automatically modify a set of connection profiles based on an event.