Provided herein are apparatus and methods for protecting radio frequency (RF) amplifiers from overdrive. In certain configurations, an RF amplification system includes a plurality of RF amplification stages including a first amplification stage and a second amplification stage subsequent to the first amplification stage in a signal path. The first amplification stage includes a first stage field-effect transistor (FET), and the second amplification stage includes a second stage FET and a gate-to-drain feedback circuit electrically connected between a gate and a drain of the second stage FET. The RF amplification system further includes an overdrive detection circuit that senses a drain current of the first stage FET to detect when an overdrive condition is present, and that decreases an impedance of the gate-to-drain feedback circuit in response to detection of the overdrive condition such that a gain of the second stage FET is reduced.