The present invention provides a real time communication method, a terminal device, an RTC server and an RTC system. The method includes: receiving, by a first terminal, call request information that is sent by another terminal to the first terminal and forwarded by an RTC server and, where the call request information carries a unique identifier of a WEB-based RTC application of a terminal sending the call request information; and determining, by the first terminal, whether to accept a call request according to the unique identifier of the WEB RTC of the terminal sending the call request information, if yes, sending request information for opening the WEB-based RTC application to the RTC server, and after receiving information of the WEB-based RTC application returned by the RTC server, communicating, by using the WEB-based RTC application, with the terminal sending the call request information.