The present invention relates to a wireless communication and, more specifically, to a method for transmitting an HARQ) response by a UE in a wireless communication system, and an apparatus for the same. The method includes receiving an E-PDCCH signal on at least one of a plurality of enhanced physical downlink control channel (E-PDCCH) sets, each E-PDCCH set including a plurality of resources units indexed per E-PDCCH set; and transmitting the HARQ response using a physical uplink control channel (PUCCH) resource determined using the index of the first resource unit among one or more resource units carrying the E-PDCCH signal, wherein the index of the first resource unit is determined on the basis of the E-PDCCH set having the lowest index among the plurality of E-PDCCH sets when specific conditions are satisfied.