Invention Grant
- Patent Title: 4-alkynyl imidazole derivative and medicine comprising same as active ingredient
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Application No.: US15414200Application Date: 2017-01-24
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Publication No.: US09855257B2Publication Date: 2018-01-02
- Inventor: Satoru Ikegami , Atsushi Watanabe , Kimio Hirano , Tadashi Ohyama
- Applicant: KAKEN PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Bunkyo-ku, Tokyo
- Assignee: KAKEN PHARMACEUTICAL CO., LTD.
- Current Assignee: KAKEN PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Bunkyo-ku, Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2013-123968 20130612
- Main IPC: A61K31/4174
- IPC: A61K31/4174 ; A61K31/4439 ; A61K31/4178 ; A61K31/4245 ; A61K31/4164
Abstract:
There are provided 4-alkynylimidazole derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof; the derivatives have a superior EP4 receptor antagonistic action and are useful as pharmaceuticals for the treatment of diseases associated with the EP4 receptor, for example, as anti-inflammatory and/or analgesic drugs for inflammatory diseases and diseases that involve various kinds of pains, and further as pharmaceuticals for the treatment of immune diseases that result from inflammations as evoked by tissue destruction due to the activation of Th1 cells and/or Th17 cells:
Public/Granted literature
- US20170128431A1 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT Public/Granted day:2017-05-11
Information query
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