The present application provides a composition comprising a core formed by gold nanoparticle, a compound of Formula (I): wherein dashed lines in Formula (I) represent (i) with or without an attachment of benzol group, (ii) a delocalized bond where shown within a ring; R1 is hydrogen or a halogen; R2 is a linker selected from C6-20 alkyl or polyethylene glycol; R3 is C1-20 alkyl, C1-20 substituted alkyl, hexadecanyl amido, pyridinyl, benzyl or pyrimidinyl; and a compound of Formula (II): wherein dashed lines, R1, R2 and R3 are defined as in Formula (II), and M is a metal. The composition has an inhibition ability against a cancer.