Invention Grant
- Patent Title: Composition and method to improve the therapeutic effect of stem cells
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Application No.: US13989708Application Date: 2011-11-28
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Publication No.: US09855300B2Publication Date: 2018-01-02
- Inventor: Lino Da Silva Ferreira , Dora Cristina Dos Santos Pedroso
- Applicant: Lino Da Silva Ferreira , Dora Cristina Dos Santos Pedroso
- Applicant Address: PT Cantanhede
- Assignee: CRIOESTAMINAL, SAÚDE E TECNOLOGIA, SA.
- Current Assignee: CRIOESTAMINAL, SAÚDE E TECNOLOGIA, SA.
- Current Assignee Address: PT Cantanhede
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Priority: PT105406 20101126
- International Application: PCT/IB2011/055342 WO 20111128
- International Announcement: WO2012/070032 WO 20120531
- Main IPC: A61K35/51
- IPC: A61K35/51 ; C12N5/0789 ; A61L26/00 ; A61L27/34 ; C12N5/071 ; A61L27/38 ; A61L27/52 ; A61K35/12
Abstract:
The invention relates to a composition and method used for injuries treatment with a surprisingly therapeutic effect. This composition comprises a population of cells derived from human umbilical cord blood which expresses one of the following markers: CD34, CD45, and CD31; a population of CD34+ derived endothelial cells; and a biomimetic gel, preferably fibrin. The method for obtaining the composition comprises the derivation of a population of endothelial cells from CD34+ cells and then a co-culture of a CD34+ cells with CD34+-derived endothelial cells within a biomimetic gel.
Public/Granted literature
- US20140147420A1 COMPOSITION AND METHOD TO IMPROVE THE THERAPEUTIC EFFECT OF STEM CELLS Public/Granted day:2014-05-29
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