An air separation module including a canister defining an interior chamber and having a first port at a first end and a second port at a second end, the canister configured to permit fluid to pass from the first port to the second port through the interior chamber, a first end cap located proximal to the first end of the canister and configured to releasably retain the first end of the canister, a second end cap located proximal to the second end of the canister and configured to releasably retain the second end of the canister, and a collar movably configured on the second end of the canister and configured to move from a first position to a second position, wherein the first position defines an engagement between the collar and the second end cap, and the second position defines a disengagement between the collar and the second end cap.