Systems and methods are provided for collision prevention One embodiment is an apparatus that includes a robot. The robot includes an end effector that operates within a manufacturing cell, and actuators defining a kinematic chain that reorients the end effector within the manufacturing cell. The robot also includes an imaging system mounted with the end effector, and a controller. The controller is able to direct the actuators to orient the imaging system towards the mirror, to acquire a point cloud of 3D positions by operating the imaging system to scan an image in the mirror, and to revise the 3D positions in the point cloud by folding the 3D positions about a surface defined by the mirror. The robot is also able to determine a volume occupied by the robot within the manufacturing cell, and to direct the robot to operate based on the volume to prevent collisions.