A railroad locomotive monitoring system configuration system for a plurality of trains comprising: a monitoring system, and an on-board computer programmed or configured to: determine or receive railroad locomotive data; determine or receive railroad operation data; determine or receive configuration data; and based at least partially on at least a portion of the railroad locomotive data, at least a portion of the railroad operation data, and at least a portion of the configuration data, automatically configure at least one setting of the at least one component of the monitoring system.