Invention Grant
![(5,6-dihydro)pyrimido[4,5-E]indolizines](/docs/US/2018-01-02/US09856258B2/abs.jpg.600x600.jpg)
- Patent Title: (5,6-dihydro)pyrimido[4,5-E]indolizines
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Application No.: US15128874Application Date: 2015-03-30
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Publication No.: US09856258B2Publication Date: 2018-01-02
- Inventor: Adrianus Petrus Antonius De Man , Rogier Christian Buijsman , Jan Gerard Sterrenburg , Joost Cornelis Marinus Uitdehaag , Joeri Johannes Petrus De Wit , Guido Jenny Rudolf Zaman
- Applicant: NETHERLANDS TRANSLATIONAL RESEARCH CENTER B.V.
- Applicant Address: NL Oss
- Assignee: NETHERLANDS TRANSLATIONAL RESEARCH CENTER B.V.
- Current Assignee: NETHERLANDS TRANSLATIONAL RESEARCH CENTER B.V.
- Current Assignee Address: NL Oss
- Agency: Oliff PLC
- Priority: EP14163734 20140407; EP15153207 20150130
- International Application: PCT/EP2015/056839 WO 20150330
- International Announcement: WO2015/155042 WO 20151015
- Main IPC: C07D471/14
- IPC: C07D471/14
![(5,6-dihydro)pyrimido[4,5-E]indolizines](/abs-image/US/2018/01/02/US09856258B2/abs.jpg.150x150.jpg)
Abstract:
A compound of Formula I: wherein, R1 and R2 independently are selected from the group consisting of optionally substituted (6-10C)aryl and (1-5C)heteroaryl groups. The compounds can be used in pharmaceutical compositions, in particular in the treatment of cancer.
Public/Granted literature
- US20170096432A1 (5,6-DIHYDRO)PYRIMIDO[4,5-E]INDOLIZINES Public/Granted day:2017-04-06
Information query
