Invention Grant
![Analogues of 4H-pyrazolo[1,5-a] benzimidazole compound as PARP inhibitors](/docs/US/2018-01-02/US09856262B2/abs.jpg.600x600.jpg)
- Patent Title: Analogues of 4H-pyrazolo[1,5-a] benzimidazole compound as PARP inhibitors
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Application No.: US15302588Application Date: 2015-03-30
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Publication No.: US09856262B2Publication Date: 2018-01-02
- Inventor: Xuehai Wang , Zhaozhong Ding , Yong Xu , Shuhui Chen , Lie Li , Gang Li , Ronghua Tu , Cailin Wang , Yang Yue , Zhibo Zhang , Hailiang Chen , Wenjie Sun , Lu Huang
- Applicant: HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE INC. , HUMANWELL HEALTHCARE (GROUP) CO., LTD. , MEDSHINE DISCOVERY INC.
- Applicant Address: CN Wuhan, Hubei CN Wuhan, Hubei CN Nanjing, Jiangsu
- Assignee: Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.,Humanwell Healthcare (Group) Co., Ltd.,Medshine Discovery Inc.
- Current Assignee: Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.,Humanwell Healthcare (Group) Co., Ltd.,Medshine Discovery Inc.
- Current Assignee Address: CN Wuhan, Hubei CN Wuhan, Hubei CN Nanjing, Jiangsu
- Agency: Harness, Dickey & Pierce P.L.C.
- Priority: CN201410144173 20140410; CN201510113090 20150313
- International Application: PCT/CN2015/075363 WO 20150330
- International Announcement: WO2015/154630 WO 20151015
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D519/00
![Analogues of 4H-pyrazolo[1,5-a] benzimidazole compound as PARP inhibitors](/abs-image/US/2018/01/02/US09856262B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed is a series of analogs of 4H-pyrazolo[1,5-α]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.
Public/Granted literature
- US20170029430A1 ANALOGUES OF 4H-PYRAZOLO[1,5-a] BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS Public/Granted day:2017-02-02
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