Invention Grant
- Patent Title: Hypoallergen
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Application No.: US14112207Application Date: 2012-04-18
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Publication No.: US09856296B2Publication Date: 2018-01-02
- Inventor: Kristiina Takkinen , Marja-Leena Laukkanen , Hans Söderlund , Sirpa Jylhä , Heidi Holkeri , Merja Niemi , Janne Jänis , Juha Rouvinen
- Applicant: Kristiina Takkinen , Marja-Leena Laukkanen , Hans Söderlund , Sirpa Jylhä , Heidi Holkeri , Merja Niemi , Janne Jänis , Juha Rouvinen
- Applicant Address: FI Helsinki
- Assignee: DESENTUM OY
- Current Assignee: DESENTUM OY
- Current Assignee Address: FI Helsinki
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: FI20115374 20110418
- International Application: PCT/EP2012/057046 WO 20120418
- International Announcement: WO2012/143374 WO 20121026
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/35 ; A61K39/36 ; C07K1/00 ; C07K14/00 ; C07K17/00 ; C07K14/415
Abstract:
The present invention provides mutant polypeptides useful as hypoallergens. More specifically the present invention provides mutant Bet v 1 proteins and the use of such polypeptides as hypoallergens for desensitizing against birch pollen allergies. Furthermore, the invention provides vaccine formulations comprising such polypeptides; the use of such formulations; and to methods of vaccination against birch pollen allergy.
Public/Granted literature
- US20140037663A1 HYPOALLERGEN Public/Granted day:2014-02-06
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