Invention Grant
- Patent Title: Soluble monomeric anti-Mullerian hormone receptor type II fusion proteins and uses thereof
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Application No.: US15115969Application Date: 2015-02-02
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Publication No.: US09856307B2Publication Date: 2018-01-02
- Inventor: Nathalie Di Clemente , Richard Cate
- Applicant: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ PARIS—SUD
- Applicant Address: FR Paris FR Orsay
- Assignee: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE),UNIVERSITÉ PARIS—SUD
- Current Assignee: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE),UNIVERSITÉ PARIS—SUD
- Current Assignee Address: FR Paris FR Orsay
- Agency: Witham, Curtis & Cook, P.C.
- Priority: EP14153715 20140203
- International Application: PCT/EP2015/052075 WO 20150202
- International Announcement: WO2015/114142 WO 20150806
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/574 ; G01N33/74 ; C07K14/72 ; A61K38/00
Abstract:
The present invention relates to soluble monomeric Anti-Mullerian Hormone Receptor type II (AMHRII) fusion proteins and uses thereof, in particular for detection or quantification of the bioactive cleaved form of Anti-Müillerian Hormone in a sample. In particular, the present invention relates to a soluble monomeric AMHRII fusion protein wherein one AMHRII extracellular domain is fused to a heterologous polypeptide. A further aspect of the present invention relates to a method for detecting or quantifying the presence of bioactive cleaved AMH in a sample, said method comprising contacting the sample with a soluble monomeric AMHRII fusion protein of the invention.
Public/Granted literature
- US20170166625A1 SOLUBLE MONOMERIC ANTI-MULLERIAN HORMONE RECEPTOR TYPE II FUSION PROTEINS AND USES THEREOF Public/Granted day:2017-06-15
Information query
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