Invention Grant
- Patent Title: Nucleic acids encoding synthetic scaffolds and host cells genetically modified with the nucleic acids
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Application No.: US14315102Application Date: 2014-06-25
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Publication No.: US09856460B2Publication Date: 2018-01-02
- Inventor: John E. Dueber , Jay D. Keasling , Gabriel C. Wu , Ghulam Reza K. Malmirchegini
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic Field & Francis, LLP
- Agent Paula A. Borden
- Main IPC: C12N15/52
- IPC: C12N15/52 ; C12N15/62 ; C12N15/63 ; C07H21/00 ; C07K2/00 ; C12N15/10 ; C12N9/00 ; C07K19/00
Abstract:
The present invention provides methods of producing a product or product precursor of a biosynthetic pathway in a genetically modified host cell. The present invention also provides genetically modified host cells comprising nucleic acids encoding a scaffold polypeptide and nucleic acids comprising nucleotide sequences encoding two or more enzymes in a biosynthetic pathway. The present invention further provides nucleic acids comprising nucleotide sequences encoding scaffold polypeptides, for use in a subject method.
Public/Granted literature
- US20140370595A1 Use of Synthetic Scaffolds for the Production of Biosynthetic Pathway Products Public/Granted day:2014-12-18
Information query
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