Invention Grant
- Patent Title: MicroRNA treatment of fibrosis
-
Application No.: US15235682Application Date: 2016-08-12
-
Publication No.: US09856481B2Publication Date: 2018-01-02
- Inventor: Ann Harris , Lindsay R. Stolzenburg
- Applicant: ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO
- Applicant Address: US IL Chicago
- Assignee: Ann & Robert H. Lurie Children's Hospital
- Current Assignee: Ann & Robert H. Lurie Children's Hospital
- Current Assignee Address: US IL Chicago
- Agency: Casimir Jones SC
- Agent David W. Staple
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K48/00
Abstract:
Provided herein are microRNAs that target transforming growth factor beta (TGF-β) receptors and attenuate pathways of fibrosis. In particular, microRNA-1343 reduces expression of TGFBR1 and TGFBR2, decreases TGF-β signaling, represses pathways of fibrosis, and treats fibrotic diseases.
Public/Granted literature
- US20170067061A1 MICRORNA TREATMENT OF FIBROSIS Public/Granted day:2017-03-09
Information query
IPC分类:
