A computer-implemented method of performing physical synthesis in a chip design process using hierarchical wire-pin co-optimization, a system, and a computer program product are described. Aspects include providing an indication of candidate pins among a plurality of pins of a plurality of macros that may be moved, and providing constraints on a range of movement of one or more of the plurality of pins. Aspects also include performing macro-level physical synthesis at each of the plurality of macros based on the candidate pins and the constraints to generate pin locations and timing results.