A multi-tier interference canceler includes a first canceler, a second canceler, and a third canceler. The first canceler samples radio frequency (RF) interference generated from a linear signal using a non-linear process. The RF interference includes linear interference and non-linear interference. The first canceler cancels the linear interference from the sampled RF interference based on the linear signal to produce a first non-linear interference sample. The second canceler receives an amplitude scaled, time-shifted version of the RF interference and cancels the linear interference from the received RF interference based on the linear signal to produce a second non-linear interference sample. The third canceler cancels the non-linear interference from the second non-linear interference sample using the first non-linear interference sample, to produce a receive signal that is substantially free of the non-linear interference and the linear interference.