Concepts and technologies are described herein for dynamic bundling of uplink data sessions based upon network signaling conditions and application interactivity states. According to one aspect disclosed herein, a mobile device can receive signaling load information from a base station. The mobile device can determine a characteristic of an uplink data flow request. The mobile device can determine whether the uplink data flow request should be bundled based, at least in part, upon the signaling load information and the characteristic of the uplink data flow request.