Invention Grant
- Patent Title: Treatment of pulmonary arterial hypertension with leukotriene inhibitors
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Application No.: US14954789Application Date: 2015-11-30
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Publication No.: US09861601B2Publication Date: 2018-01-09
- Inventor: Mark R. Nicolls , Wen Tian , Jayakumar Rajadas
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CT Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CT Stanford
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- Main IPC: A61K31/198
- IPC: A61K31/198 ; A61K9/00 ; A61K31/428 ; A61K31/216 ; A61K31/222 ; A61K45/06 ; A61K31/197 ; A61K31/40

Abstract:
Pulmonary arterial hypertension (PAH) can be prevented in persons susceptible to the diseases and PAH patients can be treated by administering an effective dose of a leukotriene inhibitor. Suitable inhibitors include leukotriene A4 hydrolase (LTA4H) inhibitors, leukotriene B4 receptor (BLT1/BLT2) antagonists, 5-lipoxygenase (5-LO) inhibitors, and 5-lipoxgygenase activating protein (FLAP) inhibitors.
Public/Granted literature
- US20160193168A1 Treatment of Pulmonary Arterial Hypertension with Leukotriene Inhibitors Public/Granted day:2016-07-07
Information query
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