Invention Grant
- Patent Title: Methods and pharmaceutical compositions for the treatment of beta-thalassemias
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Application No.: US15039230Application Date: 2014-11-28
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Publication No.: US09861615B2Publication Date: 2018-01-09
- Inventor: Olivier Hermine , Flavia Guillem , Jean-Benoit Arlet , Genevieve Courtois
- Applicant: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE PARIS DESCARTES , ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP) , FONDATION IMAGINE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- Applicant Address: FR Paris FR Paris FR Paris FR Paris FR Paris
- Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale),Universite Paris Decartes,Assistance Publique-Hopitaux de Paris (APHP),Fondation Imagine,Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale),Universite Paris Decartes,Assistance Publique-Hopitaux de Paris (APHP),Fondation Imagine,Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR Paris FR Paris FR Paris FR Paris FR Paris
- Agency: Whitham Curtis & Cook, PC
- Priority: EP13306628 20131128
- International Application: PCT/EP2014/075980 WO 20141128
- International Announcement: WO2015/079031 WO 20150604
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; A61K31/497 ; A61K31/397 ; A61K31/535 ; C07D239/42 ; A61K31/55 ; A61K31/44 ; A61K31/445 ; A61K31/495 ; A61K31/41 ; A61K31/4196 ; A61K31/4245 ; A61K31/433 ; A61K31/4439 ; A61K31/454 ; A61K31/5377 ; G01N33/50

Abstract:
The present invention relates to methods and pharmaceutical compositions for the treatment of beta-thalassemias. In particular, the present invention relates to an XPO1 inhibitor for use in a method for treating beta-thalassemia in a subject in need thereof.
Public/Granted literature
- US20170020847A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BETA-THALASSEMIAS Public/Granted day:2017-01-26
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