Invention Grant
- Patent Title: Thiazoles as modulators of RORγt
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Application No.: US14927501Application Date: 2015-10-30
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Publication No.: US09861618B2Publication Date: 2018-01-09
- Inventor: Steven Goldberg , Christoph Steeneck , Christian Gege , Olaf Kinzel , Gerald Kleymann , Thomas Hoffmann
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Yuriy P. Stercho
- Main IPC: A61K31/426
- IPC: A61K31/426 ; C07D417/04 ; A61K31/427 ; A61K45/06 ; C07D417/14 ; A61K31/5377 ; A61K31/4725 ; A61K31/454 ; A61K31/433 ; C07D277/30 ; A61K31/506

Abstract:
The present invention comprises compounds of Formula I wherein: R1, R2, R3, R4, R5, R7, R8, and are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
Public/Granted literature
- US20160120850A1 THIAZOLES AS MODULATORS OF RORyt Public/Granted day:2016-05-05
Information query
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