Invention Grant
![Salts and polymorphs of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one](/docs/US/2018-01-09/US09861638B2/abs.jpg.600x600.jpg)
- Patent Title: Salts and polymorphs of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one
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Application No.: US14698463Application Date: 2015-04-28
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Publication No.: US09861638B2Publication Date: 2018-01-09
- Inventor: Patricia Ann Basford , Anthony Michael Campeta , Adam Gillmore , Matthew Cameron Jones , Eleftherios Kougoulos , Suman Luthra , Robert Walton
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: PFIZER INC.
- Current Assignee: PFIZER INC.
- Current Assignee Address: US NY New York
- Agency: Swanson & Bratschun, L.L.C.
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D487/06 ; C07C57/145 ; C07C309/19 ; A61K45/06
![Salts and polymorphs of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one](/abs-image/US/2018/01/09/US09861638B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.
Public/Granted literature
- US20150238504A1 SALTS AND POLYMORPHS OF 8-FLUORO-2--1,3,4,5-TETRAHYDRO-6H-AZEPINO[5,4,3-CD]INDOL-6-ONE Public/Granted day:2015-08-27
Information query
