Invention Grant
- Patent Title: Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
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Application No.: US15160885Application Date: 2016-05-20
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Publication No.: US09862687B2Publication Date: 2018-01-09
- Inventor: Roy Wendell Ware, Jr. , Aaron Leigh Downey
- Applicant: Chimerix Inc.
- Applicant Address: US NC Durham
- Assignee: Chimerix, Inc.
- Current Assignee: Chimerix, Inc.
- Current Assignee Address: US NC Durham
- Agency: Cooley LLP
- Agent Ivor R. Elrifi; Heidi A. Erlacher
- Main IPC: C07D239/47
- IPC: C07D239/47 ; C07F9/6512 ; C07F9/53

Abstract:
The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
Public/Granted literature
- US20160264531A1 MORPHIC FORMS OF HEXADECYLOXYPROPYL-PHOSPHONATE ESTERS AND METHODS OF SYNTHESIS THEREOF Public/Granted day:2016-09-15
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