Invention Grant
- Patent Title: TrkA kinase inhibitors, compositions and methods thereof
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Application No.: US15128793Application Date: 2015-03-23
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Publication No.: US09862707B2Publication Date: 2018-01-09
- Inventor: Helen Mitchell , Harold B. Wood , Chun Sing Li , Qinghua Mao , Zhiqi Qi
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Sylvia A. Ayler; John C. Todaro
- Priority: CNPCT/CN2014/074143 20140326
- International Application: PCT/US2015/021952 WO 20150323
- International Announcement: WO2015/148354 WO 20151001
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D471/04 ; C07D403/14 ; C07D487/04 ; C07D401/12
Abstract:
The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
Public/Granted literature
- US20170107204A1 TRKA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF Public/Granted day:2017-04-20
Information query
