- Patent Title: Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
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Application No.: US15303890Application Date: 2014-04-24
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Publication No.: US09862711B2Publication Date: 2018-01-09
- Inventor: Benjamin Richard Bellenie , Ian Bruce , Andrew James Culshaw , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
- Applicant: Benjamin Richard Bellenie , Ian Bruce , Andrew James Culshaw , Gregory John Hollingworth , James Neef , Matthew Spendiff , Simon James Watson
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Lian Ouyang
- International Application: PCT/IB2014/060991 WO 20140424
- International Announcement: WO2015/162461 WO 20151029
- Main IPC: C07D417/04
- IPC: C07D417/04 ; C07D401/04 ; C07D403/04 ; C07D409/04 ; C07D405/14 ; C07D403/14 ; A61K31/5377 ; A61K31/497
Abstract:
The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.
Public/Granted literature
- US20170029414A1 PYRAZINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS Public/Granted day:2017-02-02
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