- Patent Title: Tricyclic nucleosides and oligomeric compounds prepared therefrom
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Application No.: US14769567Application Date: 2014-03-14
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Publication No.: US09862742B2Publication Date: 2018-01-09
- Inventor: Christian Leumann
- Applicant: UNIVERSITAT BERN
- Applicant Address: CH Bern
- Assignee: UNIVERSITÄT BERN
- Current Assignee: UNIVERSITÄT BERN
- Current Assignee Address: CH Bern
- Agency: Medler Ferro Woodhouse & Mills PLLC
- Priority: EP13159651 20130315
- International Application: PCT/EP2014/055211 WO 20140314
- International Announcement: WO2014/140348 WO 20140918
- Main IPC: C07H19/10
- IPC: C07H19/10 ; C07H19/06 ; C07H21/00

Abstract:
The present invention provides fluorine substituted tricyclic nucleosides of formula (I) wherein: the substituents are as defined in the claims. The present invention further provides oligomeric compounds prepared therefrom. Incorporation of one or more of the tricyclic nucleosides into an oligomeric compound enhances one or more properties of the oligomeric compound. Such oligomeric compounds can also be included in double stranded compositions.
Public/Granted literature
- US20160002280A1 TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM Public/Granted day:2016-01-07
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